NR4A3 antibody (AA 414-521)

Catalog No. ABIN521726

There are 2+ publications for this product available. The Mouse Monoclonal anti-NR4A3 antibody is suitable to detect NR4A3 in samples from Human. It has been validated for WB, ELISA and IF.

Quick Overview for NR4A3 antibody (AA 414-521) (ABIN521726)

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This NR4A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 1E11

Product Details anti-NR4A3 Antibody

Binding Specificity: AA 414-521

Purpose: Mouse monoclonal antibody raised against a partial recombinant NR4A3.

Sequence: LDYSRYCPTD QAAAGTDAEH VQQFYNLLTA SIDVSRSWAE KIPGFTDLPK EDQTLLIESA FLELFVLRLS IRSNTAEDKF VFCNGLVLHR LQCLRGFGEW LDSIKDFS

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: NR4A3 (NP_008912, 414 a.a. ~ 521 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-NR4A3 antibody (ABIN521726)

Alonso, Galán, Martí-Pàmies, Romero, Camacho, Rodríguez, Martínez-González: "NOR-1/NR4A3 regulates the cellular inhibitor of apoptosis 2 (cIAP2) in vascular cells: role in the survival response to hypoxic stress." in: Scientific reports, Vol. 6, pp. 34056, (2016) (PubMed).

Rodríguez-Calvo, Guadall, Calvayrac, Navarro, Alonso, Ferrán, de Diego, Muniesa, Osada, Rodríguez, Martínez-González: "Over-expression of neuron-derived orphan receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury." in: Human molecular genetics, Vol. 22, Issue 10, pp. 1949-59, (2013) (PubMed).

Target Details for NR4A3

Target: NR4A3 (Nuclear Receptor Subfamily 4, Group A, Member 3 (NR4A3))

Alternative Name: NR4A3

Background: Full Gene Name: nuclear receptor subfamily 4, group A, member 3
Synonyms: CHN,CSMF,MINOR,NOR1,TEC

Gene ID: 8013

NCBI Accession: NM_006981

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway