NPHP4 antibody (N-Term)

Catalog No. ABIN5515647

Product Details anti-NPHP4 Antibody

Target: NPHP4 (Nephronophthisis 4 (NPHP4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VSGPKVERRP SRKPPTSPSS PPAPVPRVLA APQNSPVGPG LSISQLAASP

Characteristics: This is a rabbit polyclonal antibody against NPHP4. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NPHP4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPHP4

Target: NPHP4 (Nephronophthisis 4 (NPHP4))

Alternative Name: NPHP4 (NPHP4 Products)

Synonyms: NPHP4 antibody, POC10 antibody, SLSN4 antibody, 4930564O18Rik antibody, nmf192 antibody, nephrocystin 4 antibody, nephrocystin-4 antibody, nephronophthisis 4 (juvenile) homolog (human) antibody, NPHP4 antibody, LOC100184720 antibody, Nphp4 antibody

Background: This gene encodes a protein involved in renal tubular development and function. This protein interacts with nephrocystin, and belongs to a multifunctional complex that is localized to actin- and microtubule-based structures. Mutations in this gene are associated with nephronophthisis type 4, a renal disease, and with Senior-Loken syndrome type 4, a combination of nephronophthisis and retinitis pigmentosa. Alternative splicing results in multiple transcript variants.

Alias Symbols: NPHP4, KIAA0673,

Protein Interaction Partner: UBC, CEP164, DDB1, LATS1, NPHP1, NPHP4, RPGRIP1,

Protein Size: 1426

Gene ID: 261734

NCBI Accession: XP_006710628

UniProt: O75161