FOXC2 antibody (C-Term)

Catalog No. ABIN374337

Product Details anti-FOXC2 Antibody

Target: FOXC2 (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This FOXC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Sequence: RHAAPYSYDC TKY

Specificity: This antibody detects FOXC2 / FKHL14 / MFH1 at C-term.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from C Terminus of the protein sequence according to NP_005242.1 Genename: FOXC2

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 8000. Western blot: 1-3 μg/mL. Approx 50-55 kDa band observed in Human Breast Cancer lysates(calculated MW of 53.5 kDa according to NP_005242.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FOXC2

Target: FOXC2 (Forkhead Box C2 (MFH-1, Mesenchyme Forkhead 1) (FOXC2))

Alternative Name: FOXC2 / FKHL14 / MFH1 (FOXC2 Products)

Synonyms: FKHL14 antibody, LD antibody, MFH-1 antibody, MFH1 antibody, Fkh14 antibody, Hfhbf3 antibody, Mfh1 antibody, Fkhl14 antibody, FOXC2 antibody, Foxc2 antibody, XFD-4 antibody, fd-4 antibody, fd-4' antibody, fkh7 antibody, foxc2b antibody, foxc2 antibody, forkhead box C2 antibody, forkhead box C2 (MFH-1, mesenchyme forkhead 1) antibody, forkhead box C2 S homeolog antibody, forkhead box C2 L homeolog antibody, forkhead box protein C2 antibody, FOXC2 antibody, Foxc2 antibody, foxc2.S antibody, foxc2.L antibody, LOC100734751 antibody

Background: FOXC2 belongs to the forkhead family of transcription factors which is characterized by a distinct DNA binding forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in the development of mesenchymal tissues.Synonyms: FKH-14, Forkhead box protein C2, Forkhead-related protein FKHL14, MFH-1, Mesenchyme fork head protein 1, Transcription factor FKH-14

Gene ID: 2303

NCBI Accession: NP_005242

UniProt: Q99958