ATP2A3 antibody (AA 501-620)

Catalog No. ABIN559999

This Mouse Monoclonal antibody specifically detects ATP2A3 in WB, ELISA and IHC (p). It exhibits reactivity toward Human. It has been mentioned in 3+ publications

Quick Overview for ATP2A3 antibody (AA 501-620) (ABIN559999)

Target: ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATP2A3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2H3

Product Details anti-ATP2A3 Antibody

Binding Specificity: AA 501-620

Purpose: Mouse monoclonal antibody raised against a partial recombinant ATP2A3.

Sequence: TRPHPTGQGS KMFVKGAPES VIERCSSVRV GSRTAPLTPT SREQILAKIR DWGSGSDTLR CLALATRDAP PRKEDMELDD CSKFVQYETD LTFVGCVGML DPPRPEVAAC ITRCYQAGIR

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: ATP2A3 (AAH35729, 501 a.a. ~ 620 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-ATP2A3 antibody (ABIN559999)

Ait-Ghezali, Arbabian, Jeibmann, Hasselblatt, Hallaert, Van den Broecke, Gray, Brouland, Varin-Blank, Papp: "Loss of endoplasmic reticulum calcium pump expression in choroid plexus tumours." in: Neuropathology and applied neurobiology, Vol. 40, Issue 6, pp. 726-35, (2014) (PubMed).

Arbabian, Brouland, Apáti, Pászty, Heged?s, Enyedi, Chomienne, Papp: "Modulation of endoplasmic reticulum calcium pump expression during lung cancer cell differentiation." in: The FEBS journal, Vol. 280, Issue 21, pp. 5408-18, (2013) (PubMed).

Corvazier, Bredoux, Kovács, Enouf: "Expression of sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) 3 proteins in two major conformational states in native human cell membranes." in: Biochimica et biophysica acta, Vol. 1788, Issue 3, pp. 587-99, (2009) (PubMed).

Target Details for ATP2A3

Target: ATP2A3 (ATPase, Ca++ Transporting, Ubiquitous (ATP2A3))

Alternative Name: ATP2A3

Background: Full Gene Name: ATPase, Ca++ transporting, ubiquitous
Synonyms: SERCA3

Gene ID: 489

Pathways: Myometrial Relaxation and Contraction, Ribonucleoside Biosynthetic Process