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serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79) antibody

Details for Product No. ABIN562978
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Antigen
Synonyms SPINK1, Psti, Spink3, PCTT, PSTI, TATI, TCP, Psti-1, Spink1, Tilp
Epitope
AA 24-79
(3), (2), (2), (1), (1)
Reactivity
Human
(34), (15), (4)
Host
Mouse
(40), (6), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), ELISA, Immunoprecipitation (IP)
(28), (20), (16), (7), (4), (3), (2), (1), (1), (1)
Pubmed 5 references available
Quantity 100 µg
Shipping to United States (Change)
Availability Will be delivered in 11 to 12 Business Days
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Catalog No. ABIN562978
394.24 $
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Immunogen SPINK1 (AAH25790, 24 a.a. ~ 79 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence: DSLGREAKCYNELNGCTKIY DPVCGTDGNTYPNECVLCFE NRKRQTSILIQKSGPC
Clone 4D4
Isotype IgG2a kappa
Characteristics Mouse monoclonal antibody raised against a partial recombinant SPINK1.
Alternative Name SPINK1
Background Gene: serine peptidase inhibitor, Kazal type 1
Synonyms: PCTT, PSTI, Spink3, TATI
Gene ID 6690, BC025790
Research Area Proteolysis / Ubiquitin
Application Notes Application specialization: Recombinant protein, Tissue lysate
Restrictions For Research Use only
Buffer 1x PBS, pH 7.2
Storage -20 °C
Storage Comment Store at -20 °C or lower. Aliquot to avoid repeated freezing and thawing.
Supplier Images
anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79) antibody Immunoperoxidase of monoclonal antibody to SPINK1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 1 µg/mL]
anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79) antibody (2) SPINK1 monoclonal antibody (M01), clone 4D4. Western Blot analysis of SPINK1 expression in human pancreas.
anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79) antibody (3) Immunoprecipitation of SPINK1 transfected lysate using anti-SPINK1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SPINK1 MaxPab rabbit polyclonal antibody.
anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79) antibody (4) Detection limit for recombinant GST tagged SPINK1 is 0.03 ng/mL as a capture antibody.
anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (AA 24-79) antibody (5) Western Blot detection against Immunogen (31.9 KDa) .
Product cited in: Tomlins, Rhodes, Yu et al.: "The role of SPINK1 in ETS rearrangement-negative prostate cancers." in: Cancer cell, Vol. 13, Issue 6, pp. 519-28, 2008 (PubMed).

Han, Mehra, Suleman et al.: "Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 22, Issue 9, pp. 1176-85, 2009 (PubMed).

Rink, Park, Volkmer et al.: "Loss of SPINK1 expression is associated with unfavorable outcomes in urothelial carcinoma of the bladder after radical cystectomy." in: Urologic oncology, 2012 (PubMed).

Bhalla, Kunju, Tomlins et al.: "Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 6, pp. 835-48, 2013 (PubMed).

Smith, Palanisamy, Zuhlke et al.: "HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey." in: The American journal of surgical pathology, Vol. 38, Issue 5, pp. 615-26, 2014 (PubMed).

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