Ephrin A1 antibody (Internal Region)

Catalog No. ABIN569632

This Goat Polyclonal antibody specifically detects Ephrin A1 in WB and EIA. It exhibits reactivity toward Human, Rat, Mouse, Dog and Pig.

Quick Overview for Ephrin A1 antibody (Internal Region) (ABIN569632)

Target: Ephrin A1 (EFNA1)

Reactivity: Human, Rat, Mouse, Dog, Pig

Host: Goat

Clonality: Polyclonal

Conjugate: This Ephrin A1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Ephrin A1 Antibody

Binding Specificity: Internal Region

Sequence: C-KVTVSGKITH SP

Specificity: This antibody is expected to recognize isoform alpha (NP_004419.2) only.

Cross-Reactivity (Details): Species reactivity (expected):Human, Canine (Dog), Pig.
Species reactivity (tested):Mouse, Rat.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_004419.2. Genename: EFNA1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Ephrin A1

Target: Ephrin A1 (EFNA1)

Alternative Name: Ephrin-A1

Background: The Eph subfamily represents the largest group of receptor protein kinases identified to date. There is increasing evidence that Eph family members are involved in central nervous system function and in development. Ligands for Eph receptors include Ephrin-A1 (LERK-1/B61), identified as a ligand for the EphA2 (Eck) receptor, Ephrin-A2 (ELF-1), identified as a ligand for the EphA3 and EphA4 (Sek) receptors, ephrin-A3 (LERK-3), identified as a ligand for EphA5 (Ehk1) and EphA3 (Hek) receptors, ephrin-A4 (LERK-4), identified as a ligand for the EphA3 receptor, ephrin-A5 (AL-1), identified as a ligand for EphA5 (REK7), Ephrin-B1 (LERK-2), identified as a ligand for the EphB1 (Elk) and EphB2 (Cek5) receptors, ephrin-B2 (LERK-5), identified as a ligand for the EphB1, EphB3 (Cek10) and EphB2 receptors, and Ephrin-B3 (LERK-8), identified as a ligand for EphB1.Synonyms: EFNA1, EPH-related receptor tyrosine kinase ligand 1, EPLG1, Immediate early response protein B61, LERK-1, LERK1, TNFAIP4, Tumor necrosis factor, alpha-induced protein 4

Gene ID: 1942

NCBI Accession: NP_004419

UniProt: P20827

Pathways: RTK Signaling