GNB3 antibody (Internal Region)

Catalog No. ABIN569636

The Goat Polyclonal anti-GNB3 antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect GNB3 in samples from Human.

Quick Overview for GNB3 antibody (Internal Region) (ABIN569636)

Target: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This GNB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-GNB3 Antibody

Binding Specificity: Internal Region

Sequence: SGHDNRVSCL GVT

Specificity: This antibody is expected to recognize GNB3 and GNB4 (NP_002066.1 and NP_067642.1).

Cross-Reactivity (Details): Species reactivity (tested):Human.
Also reacts to: GNB4

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_002066.1, NP_067642.1. Genename: GNB3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GNB3

Target: GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))

Alternative Name: Transducin beta Chain 3 (GNB3)

Background: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.Synonyms: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

Molecular Weight: 37.2kDa (NP_002066.1).

Gene ID: 2784

NCBI Accession: NP_002066

UniProt: P16520

Pathways: Peptide Hormone Metabolism, Myometrial Relaxation and Contraction