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GNB3 antibody (Internal Region)
GNB3
Reactivity: Human
WB, IHC (p), EIA
Host: Goat
Polyclonal
unconjugated
Product Details anti-GNB3 Antibody
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Target
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GNB3
(Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
Binding Specificity
All epitopes for GNB3 antibodies
Internal Region
Reactivity
All reactivities for GNB3 antibodies
Human
Host
All hosts for GNB3 antibodies
Goat
Clonality
All clonalities for GNB3 antibodies
Polyclonal
Conjugate
All conjugates for GNB3 antibodies
This GNB3 antibody is un-conjugated
Application
All applications for GNB3 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequence
SGHDNRVSCL GVT
Specificity
This antibody is expected to recognize GNB3 and GNB4 (NP_002066.1 and NP_067642.1).
Cross-Reactivity (Details)
Species reactivity (tested):Human. Also reacts to: GNB4
Purification
Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide
Immunogen
Peptide with sequence from the internal region of the protein sequence according to NP_002066.1, NP_067642.1. Genename: GNB3
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for GNB3
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Target
GNB3
(Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
Alternative Name
Transducin beta Chain 3 (GNB3) (GNB3 Products )
Background
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.Synonyms: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Molecular Weight
37.2kDa (NP_002066.1).
Gene ID
2784
NCBI Accession
NP_002066
UniProt
P16520
Pathways
Peptide Hormone Metabolism , Myometrial Relaxation and Contraction
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