GNB3 antibody (AA 81-180)
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- Target See all GNB3 Antibodies
- GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
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Binding Specificity
- AA 81-180
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GNB3 antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human G protein beta 3
- Isotype
- IgG
- Top Product
- Discover our top product GNB3 Primary Antibody
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- GNB3 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 3 (GNB3))
- Alternative Name
- G protein beta 3/GNB3 (GNB3 Products)
- Synonyms
- Gnb-3 antibody, MGC68913 antibody, MGC130764 antibody, gnb3 antibody, zgc:73058 antibody, zgc:77780 antibody, wu:fk54b04 antibody, gnb3l antibody, zgc:92641 antibody, G protein subunit beta 3 antibody, guanine nucleotide binding protein (G protein), beta 3 antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3 S homeolog antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3b antibody, guanine nucleotide binding protein (G protein), beta polypeptide 3a antibody, GNB3 antibody, Gnb3 antibody, gnb3.S antibody, gnb3b antibody, gnb3a antibody
- Background
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Synonyms: Gnb3, Guanine nucleotide binding protein G protein, beta polypeptide 3, Guanine nucleotide binding protein G, Hypertension associated protein, IG, SG, Transducin beta chain 3, Tsubunit beta 3, GBB3_HUMAN.
Background: G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
- Gene ID
- 2784
- Pathways
- Peptide Hormone Metabolism, Myometrial Relaxation and Contraction
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