IKBKB antibody

Catalog No. ABIN595886

The Rabbit Polyclonal anti-IKBKB antibody is suitable to detect IKBKB in samples from Human, Mouse, Rat, Cow, Monkey, Pig, Horse, Dog and Rabbit. It has been validated for IF.

Quick Overview for IKBKB antibody (ABIN595886)

Target: IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))

Reactivity: Human, Mouse, Rat, Cow, Monkey, Pig, Horse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKBKB antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-IKBKB Antibody

Specificity: Recognizes human IKK beta. Species cross-Reactivity: mouse, rat.

Purification: Immunoaffinity purified

Immunogen: Synthetic non-phosphopeptide corresponding to human IKK-beta around the phosphorylation site of tyrosine 199 (Q-K-YP-T-V).

Type of Immunogen: Synthetic Non-phosphopeptide

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:100 - 1:200)

Usage: Suitable for use in Immunofluorescence:1:100-1:200.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS (without Mg2+, Ca2+),  pH 7.4, 150 mM sodium chloride, 0.02 % sodium azide, 50 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: May be stored at 4°C for short-term only. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Aliquots are stable for at least 1 year.

Target Details for IKBKB

Target: IKBKB (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))

Alternative Name: IKBKB / IKK2 / IKK Beta

Background: Name/Gene ID: IKBKB
Subfamily: IKAPPAB
Family: Protein Kinase

Synonyms: IKBKB, Ikk 2, IKK-B, IKK2, IKKbeta, NFKBIKB, I-kappa-B kinase 2, IKKB, I-kappa-B-kinase beta, Ikb kinase-beta, IKK Beta, IKK-beta

Gene ID: 3551

UniProt: O14920

Pathways: NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins