ABCB1 antibody (Extracellular)

Catalog No. ABIN2450190

This Mouse Monoclonal antibody specifically detects ABCB1 in WB, IHC, IHC (p), IF and FACS. It exhibits reactivity toward Human and Hamster.

Quick Overview for ABCB1 antibody (Extracellular) (ABIN2450190)

Target: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Reactivity: Human, Hamster

Host: Mouse

Clonality: Monoclonal

Conjugate: This ABCB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: F4

Product Details anti-ABCB1 Antibody

Binding Specificity: Extracellular

Specificity: Extracellular amino terminal half This epitope is resistant to formalin fixation and periodate oxidation and is different from those of other commonly known MAbs to P-glycoprotein, such as C219, JSB-1, and MRK16, which recognize an intracellular and extracellular epitope of P-glycoprotein, respectively.

Purification: Protein G purified

Immunogen: Human and hamster drug-resistant viable cells followed by crude plasma membranes.

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, IF, IHC, IHC-P (20 μg/mL), WB (1 - 2 μg/mL)

Comment:

Target Species of Antibody: Hamster

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 10  mM PBS,  pH 7.4, with 0.2 % BSA and 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Stable for 2 years when stored at 2-8°C.

Target Details for ABCB1

Target: ABCB1 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

Alternative Name: ABCB1 / MDR1 / P Glycoprotein

Background: Name/Gene ID: ABCB1
Subfamily: ATP-binding cassette - ABCB/MDR
Family: Transporter

Synonyms: ABCB1, ABC20, Abcb1b, CLCS, Colchicin sensitivity, CD243, Doxorubicin resistance, IBD13, gp170, MDR1, Multidrug resistance protein 1, P glycoprotein, P-glycoprotein 1, P-GP, CD243 antigen, PGY1

Gene ID: 5243

UniProt: P08183