HVEM antibody

Catalog No. ABIN610276

This Mouse Monoclonal antibody specifically detects HVEM in ELISA and FACS. It exhibits reactivity toward Human and has been mentioned in 2+ publications.

Quick Overview for HVEM antibody (ABIN610276)

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HVEM antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: ANC3B7

Product Details anti-HVEM Antibody

Specificity: Recombinant CD270 in EIA, and binds to CD270 present on human U-937 cell surface in Flow Cytometry.

Purification: Protein A purified

Immunogen: Recombinant human CD270(HVEM).

Type of Immunogen: Recombinant protein

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate

Preservative: Gentamicin sulfate

Precaution of Use: This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze.

References for anti-HVEM antibody (ABIN610276)

Passier, Zeng, Frey, Naya, Nicol, McKinsey, Overbeek, Richardson, Grant, Olson: "CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo." in: The Journal of clinical investigation, Vol. 105, Issue 10, pp. 1395-406, (2000) (PubMed).

Ohmstede, Bland, Merrill, Sahyoun: "Relationship of genes encoding Ca2+/calmodulin-dependent protein kinase Gr and calspermin: a gene within a gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 13, pp. 5784-8, (1991) (PubMed).

Target Details for HVEM

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Alternative Name: TNFRSF14 / CD270 / HVEM

Background: Name/Gene ID: TNFRSF14
Family: TNF Receptor

Synonyms: TNFRSF14, CD270, CD270 antigen, CD40-like protein, Herpesvirus entry mediator, Herpesvirus entry mediator A, HVEM, LIGHTR, Herpes virus entry mediator A, TR2, ATAR, HVEA

Gene ID: 8764

UniProt: Q92956

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints