TNFRSF18 antibody

Catalog No. ABIN610419

Product Details anti-TNFRSF18 Antibody

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF18 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Specificity: Human GITR in EIA and on cell surface in FACS. Preincubation of the receptor with an excess of this mAb will block binding of recombinant GITR Ligand.

Purification: Protein A purified

Immunogen: Recombinant human GITR, PHA stimulated human PBL.

Type of Immunogen: Recombinant protein

Clone: ANC5E3

Isotype: IgG3 kappa

Application Details

Application Notes: Approved: ELISA, Flo

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride

Preservative: Azide free

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References for anti-TNFRSF18 antibody (ABIN610419)

Brouet, Sonveaux, Dessy, Balligand, Feron: "Hsp90 ensures the transition from the early Ca2+-dependent to the late phosphorylation-dependent activation of the endothelial nitric-oxide synthase in vascular endothelial growth factor-exposed endothelial cells." in: The Journal of biological chemistry, Vol. 276, Issue 35, pp. 32663-9, (2001) (PubMed).

Target Details for TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Alternative Name: TNFRSF18 / GITR (TNFRSF18 Products)

Background: Name/Gene ID: TNFRSF18
Family: TNF Receptor

Synonyms: TNFRSF18, AITR, CD357, CD357 antigen, GITR, GITR-D

Gene ID: 8784

UniProt: Q9Y5U5

Pathways: Cancer Immune Checkpoints