F2R antibody (Coagulation Factor II (thrombin) Receptor) (AA 267-316)

Details for Product anti-F2R Antibody No. ABIN611146, Supplier: Log in to see
Antigen
  • f2r-a
  • par1
  • CF2R
  • HTR
  • PAR-1
  • PAR1
  • TR
  • AI482343
  • Cf2r
  • Par1
  • ThrR
  • TRGPC
  • Par-1
  • BXR
  • ONR1
  • PAR
  • PAR2
  • PARq
  • PRR
  • PXR
  • SAR
  • SXR
  • coagulation factor 2 (thrombin) receptor
  • coagulation factor II (thrombin) receptor
  • nuclear receptor subfamily 1, group I, member 2
  • f2r
  • F2R
  • F2r
  • NR1I2
Alternatives
anti-Human F2R antibody for Immunofluorescence (fixed cells)
Epitope
AA 267-316
50
15
14
13
11
9
5
5
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
184
45
25
2
2
2
2
2
1
1
1
Host
Rabbit
98
61
25
1
Clonality
Polyclonal
Conjugate
This F2R antibody is un-conjugated
6
6
5
5
4
3
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
134
89
42
34
29
26
22
13
8
2
1
1
1
1
1
Options
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Immunogen Synthetic peptide located between aa267-316 of human F2R (P25116, NP_001983). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Mouse, Rat (100%), Gibbon, Baboon, Monkey, Galago, Marmoset, Hamster, Dog, Horse (92%), Pig (85%), Rabbit (84%).

Type of Immunogen: Synthetic peptide
Specificity Human F2R / Thrombin Receptor
Predicted Reactivity Percent identity by BLAST analysis: Mouse, Rat (100%) Dog (92%) Pig (85%) Rabbit (84%).
Purification Immunoaffinity purified
Alternative Name F2R / Thrombin Receptor / PAR1 (F2R Antibody Abstract)
Background Name/Gene ID: F2R
Subfamily: Proteinase-activated
Family: GPCR

Synonyms: F2R, CF2R, Coagulation factor II receptor, PAR1, PAR-1, Thrombin receptor, TR, HTR, Protease-activated receptor 1
Gene ID 2149
NCBI Accession NP_001983
UniProt P25116
Pathways Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
Application Notes Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-F2R antibody (Coagulation Factor II (thrombin) Receptor) (AA 267-316) (ABIN611146) anti-Coagulation Factor II (thrombin) Receptor (F2R) (AA 267-316) antibody
Product cited in: Gradin, Larsson, Marklund, Gullberg: "Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells." in: The Journal of cell biology, Vol. 140, Issue 1, pp. 131-41, 1998 (PubMed).

Horwitz, Shen, He, Dittmar, Neef, Chen, Schubart: "The microtubule-destabilizing activity of metablastin (p19) is controlled by phosphorylation." in: The Journal of biological chemistry, Vol. 272, Issue 13, pp. 8129-32, 1997 (PubMed).

Larsson, Marklund, Gradin, Brattsand, Gullberg: "Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis." in: Molecular and cellular biology, Vol. 17, Issue 9, pp. 5530-9, 1997 (PubMed).