Ankyrin G antibody
Quick Overview for Ankyrin G antibody (ABIN615371)
Target
See all Ankyrin G (ANK3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- This antibody recognizes Ankyrin 3, Node Of Ranvier (ankyrin G) (ANK3).
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Cross-Reactivity (Details)
- Species reactivity (tested):Human.
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Purification
- Immunoaffinity Chromatography
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Immunogen
- ANK3 antibody was raised against synthetic peptide.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline buffer, pH ´7.3 containing 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))
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Alternative Name
- Ankyrin-3
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Background
- Ankyrins are a family of spectrin-binding protein that couple the spectrin/actin cytoskeletal network to the cytoplasmic domains of integral membrane proteins which include channels such as the anion exchanger, voltage-dependent sodium channel and the Na/K ATPase. 3 forms of ankyrin G exists, 190 kDa, 270 kDa and 480 kDa, that are localized in the axonal intial segments and the nodes of Ranvier of myelinated axons where fluxes of action potential occur and ion channels are enriched.Synonyms: ANK-3, ANK3, Ankyrin G
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Gene ID
- 288
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NCBI Accession
- NP_066267
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UniProt
- Q12955
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Pathways
- Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development
Target
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