XRCC3 antibody (AA 202-296)

Catalog No. ABIN615996

The Rabbit Polyclonal anti-XRCC3 antibody (ABIN615996) specifically detects XRCC3 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for XRCC3 antibody (AA 202-296) (ABIN615996)

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRCC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-XRCC3 Antibody

Binding Specificity: AA 202-296

Specificity: Recognizes XRCC3.
Cellular Localization: Nucleus.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 202 and 296 of Human XRCC3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) and 0.01 % Thimerosal as preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C.

Target Details for XRCC3

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Alternative Name: XRCC3

Background: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identifiedSynonyms: DNA repair protein XRCC3, X-ray repair cross-complementing protein 3

Molecular Weight: 38 kDa

Gene ID: 7517, 9606

UniProt: O43542

Pathways: DNA Damage Repair