RUVBL1 antibody

Catalog No. ABIN631717

Product Details anti-RUVBL1 Antibody

Target: RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RUVBL1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purified

Immunogen: RUVBL1 antibody was raised using a synthetic peptide corresponding to a region with amino acids KIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGV

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

RUVBL1 Blocking Peptide, catalog no. 33R-4427, is also available for use as a blocking control in assays to test for specificity of this RUVBL1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of RUVBL1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for RUVBL1

Target: RUVBL1 (RuvB-Like 1 (E. Coli) (RUVBL1))

Alternative Name: RUVBL1 (RUVBL1 Products)

Synonyms: rvb1 antibody, ecp54 antibody, tip49 antibody, nmp238 antibody, pontin antibody, tip49a antibody, xpontin antibody, pontin52 antibody, TIP49 antibody, wu:fd18e04 antibody, zpontin antibody, ECP54 antibody, INO80H antibody, NMP238 antibody, PONTIN antibody, Pontin52 antibody, RVB1 antibody, TIH1 antibody, TIP49A antibody, Tip49a antibody, 2510009G06Rik antibody, RuvB like AAA ATPase 1 antibody, RuvB-like 1 (E. coli) antibody, RuvB-like 1 antibody, RuvB like AAA ATPase 1 S homeolog antibody, RuvB-like AAA ATPase 1 antibody, RuvB-like protein 1 antibody, RUVBL1 antibody, ruvbl1 antibody, PVX_123295 antibody, Bm1_15605 antibody, ruvb1 antibody, ruvbl1.S antibody, Ruvbl1 antibody

Background: RUVBL1 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. It is the component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400.

Molecular Weight: 50 kDa (MW of target protein)

Pathways: Telomere Maintenance