Defensin beta 3 antibody (AA 23-33)

Catalog No. ABIN636242

Product Details anti-Defensin beta 3 Antibody

Target: Defensin beta 3 (DEFB3)

Binding Specificity: AA 23-33

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Defensin beta 3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity chromatography purified

Immunogen: BD3 antibody was raised in rabbit using AA 23-33 [GIINTLQKYYC] of the 5-kDa human beta-defensin-3 protein as the immunogen.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Buffer: Affinity purified IgG supplied in PBS with 0.02 % NaN3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Target Details for Defensin beta 3

Target: Defensin beta 3 (DEFB3)

Alternative Name: BD3 (DEFB3 Products)

Synonyms: BD-3 antibody, DEFB-3 antibody, DEFB103 antibody, DEFB3 antibody, HBD3 antibody, HBP-3 antibody, HBP3 antibody, hBD-3 antibody, BNBD-3 antibody, BNBD-6 antibody, BNDB-3 antibody, BNDB-6 antibody, BNDB3 antibody, DEFB103A antibody, DEFB2 antibody, DEFB6 antibody, bnbd3 antibody, defb405 antibody, defensin beta 103A antibody, defensin beta 3 antibody, beta-defensin 3 antibody, DEFB103A antibody, Defb3 antibody, DEFB3 antibody

Background: A novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, hBD-3) was isolated from human lesional psoriatic scales and cloned from keratinocytes. hBD-3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many potentially pathogenic microbes including multiresistant S. aureus and vancomycin-resistant Enterococcus faecium.

Pathways: Production of Molecular Mediator of Immune Response