TRAIL antibody

Catalog No. ABIN636583

This Rabbit Polyclonal antibody specifically detects TRAIL in WB, ELISA and InhibAb. It exhibits reactivity toward Human.

Quick Overview for TRAIL antibody (ABIN636583)

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAIL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Blocking Antibody (InhibAb)

Product Details anti-TRAIL Antibody

Purification: Purified

Immunogen: TRAIL antibody was raised in rabbit using highly pure recombinant human TRAIL/Apo2 L as the immunogen.

Application Details

Application Notes: ELISA: 0.5-2 µg/mL, Inhibition: 150 ng/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Target Details for TRAIL

Target: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Alternative Name: TRAIL

Background: TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain”, which activates the cell’s apoptotic machinery.

Molecular Weight: 20 kDa (predicted detection band MW)

Pathways: Apoptosis, Positive Regulation of Endopeptidase Activity