IL-13 antibody
Quick Overview for IL-13 antibody (ABIN640008)
Target
See all IL-13 (IL13) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Rabbit Anti-Mouse IL-13
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Specificity
- DS-PB-01088 is specific for mouse Interleukin-13 (IL-13), a 12.3kDa immunoregulatory cytokine produced primarily by activated T helper type 2 (Th2) cells and also by mast cells and NK cells. The biological properties of IL-13 include stimulation of B cell proliferation and antibody production and studies suggest that IL-13 plays an important role in the induction of the pathophysiological features of allergic asthma, independently of Immunoglobulin E and eosinophils (1).
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Characteristics
- Cytokines/Chemokines/Growth Factors/Receptors
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Purification
- Purified
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Immunogen
- Antisera to mouse IL-13 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
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Isotype
- IgG
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Application Notes
- ELISA (dilution: 0.1, 0.2 μg/mL), Western Blotting
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Restrictions
- For Research Use only
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Reconstitution
- Reconstitute with 0.1 mL distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. RayBiotech recommend that the vial is gently mixed after reconstitution. For long term storage the addition of 0.09 % sodium azide is recommended.
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Concentration
- IgG concentration 1.0 mg/ml
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Buffer
- Phosphate buffered saline pH7.4
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Storage
- -20 °C
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Storage Comment
- -20°C
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- IL-13 (IL13) (Interleukin 13 (IL13))
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Alternative Name
- Interleukin-13
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Pathways
- JAK-STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
Target
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