IDO1 antibody

Catalog No. ABIN644670

The Mouse Monoclonal anti-IDO1 antibody (ABIN644670) specifically detects IDO1 in WB and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for IDO1 antibody (ABIN644670)

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IDO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-IDO1 Antibody

Purpose: Mouse Anti-Human IIDO

Specificity: DS-MB-01673 recognizes Indoleamine-pyrrole 2,3-dioxygenase (IDO), an enzyme responsible for the catabolism of tryptophan to N-formlkynurenine and kynurenine. With the exception of tryptophan oxidase in hepatocytes, IDO is the only enzyme that degrades the amino acid tryptophan to kynurenine. Chlamydial pathogens require tryptophan for growth. IDO can lower available tryptophan in target cells leading to conversion of the pathogen to persistant forms, with significance in the progression to chronic infection with its associated pathological effects.

Characteristics: Proteases & Other Enzymes

Purification: Purified

Isotype: IgG3

Application Details

Application Notes: Immunohistology - Frozen, Western Blotting

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 100 µg of purified antibody. It is reconstituted with 100 µl of sterile PBS. Its final concentration is 1.0 mg/ml. Please avoid freeze-thaw cycles.

Storage: -20 °C

Storage Comment: -20°C

Target Details for IDO1

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Alternative Name: Indolamine 2,3-Dioxygenase (IDO)

Pathways: Activated T Cell Proliferation