BAK1 antibody

Catalog No. ABIN645850

This Goat not_set antibody specifically detects BAK1 . It exhibits reactivity toward Mouse and Rat.

Quick Overview for BAK1 antibody (ABIN645850)

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reactivity: Mouse, Rat

Host: Goat

Conjugate: This BAK1 antibody is un-conjugated

Application: Please inquire

Product Details anti-BAK1 Antibody

Specificity: The goat Anti-BAK1 antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Characteristics: Goat Anti-BAK1

Immunogen: Peptide with sequence C-ASGQGPGPPRQE, from the N Terminus of the protein sequence according to NP_001179, was used as immunogen.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Storage: -20 °C

Target Details for BAK1

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Alternative Name: BAK1

Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.

NCBI Accession: NP_001179

Pathways: Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response