Retinoid X Receptor alpha antibody

Catalog No. ABIN645871

This Goat not_set antibody specifically detects Retinoid X Receptor alpha . It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Retinoid X Receptor alpha antibody (ABIN645871)

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Reactivity: Human, Mouse, Rat

Host: Goat

Conjugate: This Retinoid X Receptor alpha antibody is un-conjugated

Application: Please inquire

Product Details anti-Retinoid X Receptor alpha Antibody

Specificity: The Goat anti-RXR alpha antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Characteristics: Goat Anti-RXR alpha

Immunogen: Peptide with sequence CQVNSSLTSPTGRGSM, from the internal region of the protein sequence according to NP_002948, was used as an immunogen.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Storage: -20 °C

Target Details for Retinoid X Receptor alpha

Target: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Alternative Name: RXR alpha

Background: Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins that exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).

NCBI Accession: NP_002948

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C