Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A) (AA 29-57), (N-Term) antibody

Details for Product No. ABIN650714
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Antigen
Synonyms fj46c12, wu:fj46c12, zgc:66106, SEMA6A, HT018, SEMA, SEMA6A1, SEMAQ, VIA, 9330158E07, A730020P05Rik, AI851735, Sema6A-1, Semaq, VIa, b2b997Clo
Epitope
AA 29-57, N-Term
(15), (14), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(61), (16), (13), (1)
Host
Rabbit
(45), (18), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (3), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(39), (25), (10), (8), (6), (5), (4), (4), (3), (2), (1), (1)
Pubmed 1 reference available
Quantity 400 μL
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Immunogen This SEMA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 AA from the N-terminal region of human SEMA6A.
Clone RB21218
Isotype Ig
Specificity This SEMA6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human SEMA6A.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SEMA6A (SEMA6A Antibody Abstract)
Background SEMA6A belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. However, the length of the cytoplasmic tail, which includes an EVL-binding site in SEMA6A and an Src-binding site in SEMA6B, suggests that these semaphorins may also function as receptors. SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. SEMA6A directly links the Ena/VASP and the semaphorin protein families since the SEMA6A protein is capable of selective binding to the protein EVL (Ena/VASP-like protein).
Synonyms: Semaphorin-6A,SEMA6A,SEMAQ, KIAA1368
Molecular Weight 114369 DA
Gene ID 57556
NCBI Accession NP_065847
UniProt Q9H2E6
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A) (AA 29-57), (N-Term) antibody SEMA6A Antibody (N-term) (ABIN650714) western blot analysis in A2058 cell line lysate...
Background publications Landers, Melki, Meininger et al.: "Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 22, pp. 9004-9, 2009 (PubMed).

Validation Images
Catalog No. ABIN650714
291.50 $
Plus shipping costs $45.00
Quantity
Price
400 μL
291.50 $

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