Syndecan 1 (SDC1) (C-Term,Lys281) antibody

Antigen: Syndecan 1 (SDC1)

Synonyms: SDC, CD138, SYND1, syndecan, Sstn, Synd, Synd1, syn-1, AA408134, AA409076, sdc, Syn1, cd138, synd1, xSyn1, syndecan1, Syndecan-1, XSyndecan-1, HSPG, SYNDECA, Syndecan, SDC1, MGC139976

Binding Site: C-Term,Lys281

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN650771

Additional Information

Alternative name: CD138

Gene ID: 6382

UniProt: P18827

Immunogen: This CD138 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273~303 amino acids from the C-terminal region of human CD138.

Isotype: Ig

Description: Other names: Syndecan-1, SYND1, CD_antigen=CD138, Flags: Precursor, SDC, SDC1

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This CD138 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273~303 amino acids from the C-terminal region of human CD138.

Molecular Weight: 32462 DA

Comments:

Background: CD138 is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Stem Cells

Restrictions: For Research Use only

Images

Western blot analysis of CD138 Antibody (C-term K281) (ABIN650771) in HepG2 cell line lysates (35ug/lane). CD138 (arrow) was detected using the purified Pab.

Publications

Product: Endo, Takino, Miyamori et al.: "Cleavage of syndecan-1 by membrane type matrix metalloproteinase-1 stimulates cell migration." in: The Journal of biological chemistry, Vol. 278, Issue 42, pp. 40764-70, 2003 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).