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FOXP3 antibody (Forkhead Box P3) (pSer418)

Details for Product anti-FOXP3 Antibody No. ABIN650867, Supplier: Log in to see
Antigen
  • foxp3
  • FOXP3
  • AIID
  • DIETER
  • IPEX
  • PIDX
  • XPID
  • JM2
  • scurfin
  • sf
  • RGD1562112
Epitope
pSer418
89
22
14
13
13
13
10
7
6
6
6
6
6
5
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
Reactivity
Human
324
185
57
22
22
21
16
12
9
8
2
2
1
1
Host
Rabbit
204
131
66
32
Clonality (Clone)
Polyclonal ()
Conjugate
This FOXP3 antibody is un-conjugated
36
30
22
19
15
13
11
10
6
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
Application
Dot Blot (DB)
240
167
141
86
38
31
29
29
18
16
15
6
5
4
2
2
2
1
1
Supplier
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Immunogen This FOXP3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S418 of human FOXP3.
Clone RB38848
Isotype Ig
Specificity This Phospho-FOXP3-S418 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding S418 of human FOXP3.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FOXP3 (FOXP3 Antibody Abstract)
Background The protein is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome.
Synonyms: Scurfin, Forkhead box protein P3,JM2, IPEX, FOXP3
Molecular Weight 47244 DA
Gene ID 50943
NCBI Accession NP_054728
UniProt Q9BZS1
Research Area Transcription Factors, Phospho-specific antibodies, Signaling, Cell Structure
Application Notes DB = 1:500
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Dot Blot (DB) image for anti-FOXP3 antibody (Forkhead Box P3) (pSer418) (ABIN650867) Dot blot analysis of anti-Phospho-FOXP3-S418 Phospho-specific Pab (ABIN650867) on nit...
Product cited in: Nie, Zheng, Li et al.: "Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-? in rheumatoid arthritis." in: Nature medicine, Vol. 19, Issue 3, pp. 322-8, 2013 (PubMed).

Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).