Protein YMEL-1 (YMEL-1) (N-Term), (AA 191-219) antibody

Details for Product No. ABIN651076
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Antigen
Epitope
N-Term, AA 191-219
(1), (1)
Reactivity
Human, Hamster
(1), (1)
Host
Rabbit
(1)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN651076
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This YMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 AA from the N-terminal region of human YMEL1.
Clone RB24746
Isotype Ig
Specificity This YMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 140-170 from the N-terminal region of human YMEL1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name YMEL1
Background YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
Synonyms: Presenilin-associated metalloprotease, PAMP, Meg-4, ATP-dependent metalloprotease FtsH1, YME1-like protein 1, ATP-dependent metalloprotease YME1L1,UNQ1868/PRO4304, YME1L, FTSH1, YME1L1
Molecular Weight 86455 DA
Gene ID 10730
UniProt Q96TA2
Research Area Signaling, Protein Modifications, Chromatin, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Protein YMEL-1 (YMEL-1) (N-Term), (AA 191-219) antibody YMEL1 Antibody (N-term) (ABIN651076) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
anti-Protein YMEL-1 (YMEL-1) (N-Term), (AA 191-219) antibody (2) Western blot analysis of YMEL1 Antibody (N-term) (ABIN651076) in HepG2 cell line lysates (35 µg/lane). YMEL1 (arrow) was detected using the purified polyclonal antibody.
anti-Protein YMEL-1 (YMEL-1) (N-Term), (AA 191-219) antibody (3) Western blot analysis of YMEL1 Antibody (N-term) (ABIN651076) in CHO cell line lysates (35 µg/lane). YMEL1 (arrow) was detected using the purified polyclonal antibody.
Background publications Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10...." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Hosts (1)
Reactivities (1), (1)
Applications (1), (1), (1)
Epitopes (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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