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Protein YMEL-1 (YMEL-1) (N-Term), (AA 191-219) antibody

Details for Product No. ABIN651076
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Antigen
Epitope
N-Term, AA 191-219
(1), (1)
Reactivity
Human, Hamster
(1), (1)
Host
Rabbit
(1)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(1), (1), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN651076
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This YMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 AA from the N-terminal region of human YMEL1.
Clone RB24746
Isotype Ig
Specificity This YMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 140-170 from the N-terminal region of human YMEL1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name YMEL1
Background YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
Synonyms: Presenilin-associated metalloprotease, PAMP, Meg-4, ATP-dependent metalloprotease FtsH1, YME1-like protein 1, ATP-dependent metalloprotease YME1L1,UNQ1868/PRO4304, YME1L, FTSH1, YME1L1
Molecular Weight 86455 DA
Gene ID 10730
UniProt Q96TA2
Research Area Signaling, Protein Modifications, Chromatin, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Protein YMEL-1 (YMEL-1) (N-Term), (AA 191-219) antibody YMEL1 Antibody (N-term) (ABIN651076) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
anti-Protein YMEL-1 (YMEL-1) (N-Term), (AA 191-219) antibody (2) Western blot analysis of YMEL1 Antibody (N-term) (ABIN651076) in HepG2 cell line lysates (35 µg/lane). YMEL1 (arrow) was detected using the purified polyclonal antibody.
anti-Protein YMEL-1 (YMEL-1) (N-Term), (AA 191-219) antibody (3) Western blot analysis of YMEL1 Antibody (N-term) (ABIN651076) in CHO cell line lysates (35 µg/lane). YMEL1 (arrow) was detected using the purified polyclonal antibody.
Background publications Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN651076
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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