S100 Calcium Binding Protein B (S100B) antibody
| Antigen | S100 Calcium Binding Protein B (S100B) |
| Synonyms | NEF, S100, S100beta |
| Clonality | Polyclonal |
| Host |
 Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Western Blotting (WB), ELISA |
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1 reference available |
| Certificates | ISO 9001:2008 |
| Catalog no. | ABIN651265 |
| Quantity | 0.1 mg (0.25 mg/ml) |
| Price | 280.50 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Alternative name | S100B |
| Gene ID | 6285 |
| UniProt | P04271 |
| Immunogen | This S100B antibody is generated from rabbits immunized with S100B recombinant protein. |
| Isotype | Ig |
| Description | Other names: S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, Protein S100-B,S100B |
| Characteristics | Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Specificity | This S100B antibody is generated from rabbits immunized with S100B recombinant protein. |
| Molecular Weight | 10713 DA |
| Comments |
Background: S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. |
Application Details
| Application Notes | The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 |
| Concentration | 0.25 mg/ml |
| Purification | Purified |
| Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by protein affinity purification. |
| Storage | Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles |
| Research Area | Cell Structure |
| Restrictions | For Research Use only |
Images
Publications
| Product |
Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).
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