S100 Calcium Binding Protein B (S100B) antibody

Details for Product No. ABIN651265
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Antigen
Synonyms AI266795, S100, S100a, NEF, S100-B, S100beta, S100P, AI850290, Bpb
Reactivity
Human, Mouse (Murine)
(129), (44), (42), (37), (13), (9), (4), (4)
Host
Rabbit
(96), (59), (4), (4), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(8), (7), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(116), (74), (52), (47), (17), (15), (15), (14), (10), (10), (8), (5), (3), (2), (1), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN651265
291.50 $
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Immunogen This S100B antibody is generated from rabbits immunized with S100B recombinant protein.
Clone RB22934
Isotype Ig
Predicted Reactivity Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name S100B
Background S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21, however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Synonyms: S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B, Protein S100-B,S100B
Molecular Weight 10713 DA
Gene ID 6285
UniProt P04271
Research Area Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-S100 Calcium Binding Protein B (S100B) antibody Western blot analysis of S100B Antibody (ABIN651265) in mouse liver tissue lysates (35 µg/lane).S100B (arrow) was detected using the purified polyclonal antibody.
anti-S100 Calcium Binding Protein B (S100B) antibody (2) S100B Antibody (ABIN651265) flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Validation Images
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