LINGO1 antibody (C-Term)

Catalog No. ABIN651289

This Rabbit Polyclonal antibody specifically detects LINGO1 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.It has been mentioned in 1 publication

Quick Overview for LINGO1 antibody (C-Term) (ABIN651289)

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15362

Product Details anti-LINGO1 Antibody

Binding Specificity: AA 575-603, C-Term

Predicted Reactivity: C, Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LINGO-1(LRRN6A) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 amino acids from the C-terminal region of human LINGO-1(LRRN6A).

Isotype: Ig Fraction

Application Details

Application Notes: IHC: 1:50. IHC: 1:125. WB: 1:1000-1:2000. IHC-P: 1:50~100. IHC: 1:250. IHC: 1:125

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-LINGO1 antibody (ABIN651289)

Towner, Jensen, Vaillant, Colman, Saunders, Giles, Wren: "Experimental validation of 5 in-silico predicted glioma biomarkers." in: Neuro-oncology, Vol. 15, Issue 12, pp. 1625-34, (2013) (PubMed).

Target Details for LINGO1

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Alternative Name: LINGO-1 (LRRN6A)

Background: LINGO-1 is functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. LINGO-1 is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.

Molecular Weight: 69101

Gene ID: 235402

NCBI Accession: NP_851419

UniProt: Q9D1T0