LINGO1 antibody (pSer596)

Catalog No. ABIN650826

The Rabbit Polyclonal anti-LINGO1 antibody (Clone RB15362) (ABIN650826) specifically detects LINGO1 in DB. The antibody is reactive with Human samples.

Quick Overview for LINGO1 antibody (pSer596) (ABIN650826)

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO1 antibody is un-conjugated

Application: Dot Blot (DB)

Clone: RB15362

Product Details anti-LINGO1 Antibody

Binding Specificity: pSer596

Predicted Reactivity: C, Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LINGO-1(LRRN6A) Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S596 of human LINGO-1(LRRN6A).

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for LINGO1

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Alternative Name: LINGO-1 (LRRN6A)

Background: LINGO-1 (LRR and Ig domain-containing Nogo Receptor interating protein) is a nervous system-specific LRR-Ig-containing protein with an important role in CNS biology. LINGO-1 was discovered in a sequence database search for human SLIT homologs that were selectively expressed in the brain. LINGO-1 is a transmembrane protein that is a component of the Nogo-66 receptor complex. It binds NgR1 and p75 and is an additional functional componenet of the NgR1/p75 signaling complex.

Molecular Weight: 69101

Gene ID: 235402

NCBI Accession: NP_851419

UniProt: Q9D1T0