LINGO1 antibody (N-Term)

Catalog No. ABIN391440

The Rabbit Polyclonal anti-LINGO1 antibody (Clone RB8949) (ABIN391440) specifically detects LINGO1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for LINGO1 antibody (N-Term) (ABIN391440)

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LINGO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB8949

Product Details anti-LINGO1 Antibody

Binding Specificity: AA 62-92, N-Term

Predicted Reactivity: C, Pr, M

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This LINGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of human LINGO1.

Isotype: Ig Fraction

Application Details

Application Notes: IHC: 1:400. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for LINGO1

Target: LINGO1 (Leucine Rich Repeat and Ig Domain Containing 1 (LINGO1))

Alternative Name: LINGO1

Background: LINGO1 is a functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. It is also an important negative regulator of oligodentrocyte differentiation and axonal myelination.

Molecular Weight: 69876

Gene ID: 84894

NCBI Accession: NP_116197

UniProt: Q96FE5