SOX2 antibody (pSer246, pSer249, pSer250, pSer251)

Catalog No. ABIN651838

This Rabbit Polyclonal antibody specifically detects SOX2 in WB. It exhibits reactivity toward Human.

Quick Overview for SOX2 antibody (pSer246, pSer249, pSer250, pSer251) (ABIN651838)

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB27268

Product Details anti-SOX2 Antibody

Binding Specificity: pSer246, pSer249, pSer250, pSer251

Predicted Reactivity: M, Sh

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Sox2-pS246-pS249-pS250--pS251 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-262 amino acids from the C-terminal region of human Sox2-pS246-pS249-pS250--pS251.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SOX2

Target: SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))

Alternative Name: SOX2

Background: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach.

Molecular Weight: 34310

Gene ID: 6657

NCBI Accession: NP_003097

UniProt: P48431

Pathways: Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis