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Tyrosine Kinase, Non-Receptor, 1 (TNK1) antibody

Antigen

Tyrosine Kinase, Non-Receptor, 1 (TNK1)

Synonyms MGC46193
Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN652385
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name TNK1
Gene ID 8711
UniProt O95364
Immunogen This TNK1 antibody is generated from rabbits immunized with TNK1 recombinant protein.
Isotype Ig
Description Other names: Non-receptor tyosine kinase
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This TNK1 antibody is generated from rabbits immunized with TNK1 recombinant protein.
Molecular Weight 71926 DA
Comments

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Application Details

Application Notes The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500
Concentration 0.25 mg/ml
Purification Purified
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Restrictions For Research Use only

Publications

Product Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).

Alternatives

Alternatives for antigen "Tyrosine Kinase, Non-Receptor, 1 (TNK1)", type "Antibodies"
Hosts Rabbit (44), Mouse (7)
Reactivities Human (42), Mouse (Murine) (33), Rat (Rattus) (27), Horse (Equine) (24), Cow (Bovine) (19), Dog (Canine) (5), Guinea Pig (5), Pig (Porcine) (5)
Applications Western Blotting (WB) (29), ELISA (21), Immunofluorescence (IF) (21), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunohistochemistry (IHC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1)
Conjugates Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1)
Epitopes pTyr277 (4), N-Term (3), C-Term (2), Center (2), AA 421-434 (1), Internal Region (1), N-Term, AA 521-434 (1), pTyr992 (1)