Tyrosine Kinase, Non-Receptor, 1 (TNK1) antibody
| Antigen | Tyrosine Kinase, Non-Receptor, 1 (TNK1) |
| Synonyms | MGC46193 |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Western Blotting (WB), ELISA |
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1 reference available |
| Certificates | ISO 9001:2008 |
| Catalog no. | ABIN652385 |
| Quantity | 0.1 mg (0.25 mg/ml) |
| Price | 280.50 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Alternative name | TNK1 |
| Gene ID | 8711 |
| UniProt | O95364 |
| Immunogen | This TNK1 antibody is generated from rabbits immunized with TNK1 recombinant protein. |
| Isotype | Ig |
| Description | Other names: Non-receptor tyosine kinase |
| Characteristics | Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |
| Specificity | This TNK1 antibody is generated from rabbits immunized with TNK1 recombinant protein. |
| Molecular Weight | 71926 DA |
| Comments |
Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. |
Application Details
| Application Notes | The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500 |
| Concentration | 0.25 mg/ml |
| Purification | Purified |
| Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles |
| Research Area | Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure |
| Restrictions | For Research Use only |
Images
| Western blot analysis of TNK1 Antibody (ABIN652385) in T47D cell line lysates (35ug/lane). TNK1 (arrow) was detected using the purified Pab. |
Publications
| Product |
Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).
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Alternatives
Alternatives for antigen "Tyrosine Kinase, Non-Receptor, 1 (TNK1)", type "Antibodies"
| Hosts | Rabbit (44), Mouse (7) |
| Reactivities | Human (42), Mouse (Murine) (33), Rat (Rattus) (27), Horse (Equine) (24), Cow (Bovine) (19), Dog (Canine) (5), Guinea Pig (5), Pig (Porcine) (5) |
| Applications | Western Blotting (WB) (29), ELISA (21), Immunofluorescence (IF) (21), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunohistochemistry (IHC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1), Immunoprecipitation (IP) (1) |
| Conjugates | Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), PE,Cy5.5 (2), Alexa Flour 488 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1) |
| Epitopes | pTyr277 (4), N-Term (3), C-Term (2), Center (2), AA 421-434 (1), Internal Region (1), N-Term, AA 521-434 (1), pTyr992 (1) |




Alternatives