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Tyrosine Kinase, Non-Receptor, 1 (TNK1) antibody

Details for Product No. ABIN652385, Supplier: Log in to see
Antigen
  • Kos1
  • Tnk1a
  • Tnk1b
  • Ack-like
Reactivity
Human
93
47
19
Host
Rabbit
89
27
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
8
8
8
7
7
7
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
97
68
37
13
10
2
2
1
1
Supplier
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Immunogen This TNK1 antibody is generated from rabbits immunized with TNK1 recombinant protein.
Clone RB23020
Isotype Ig
Specificity This TNK1 antibody is generated from rabbits immunized with TNK1 recombinant protein.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TNK1 (TNK1 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.
Synonyms: Non-receptor tyosine kinase
Molecular Weight 71926 DA
Gene ID 8711
UniProt O95364
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.43 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Tyrosine Kinase, Non-Receptor, 1 (TNK1) antibody (ABIN652385) Western blot analysis of TNK1 Antibody (ABIN652385) in T47D cell line lysates (35 µg/...
Background publications Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).