HVEM antibody (AA 210-236)

Catalog No. ABIN653038

This Rabbit Polyclonal antibody specifically detects HVEM in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for HVEM antibody (AA 210-236) (ABIN653038)

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HVEM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21524

Product Details anti-HVEM Antibody

Binding Specificity: AA 210-236

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TNFRSF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-236 amino acids from the Central region of human TNFRSF14.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HVEM

Target: HVEM (TNFRSF14) (Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14))

Alternative Name: TNFRSF14

Background: TNFRSF14 is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.

Molecular Weight: 30392

Gene ID: 8764

NCBI Accession: NP_003811

UniProt: Q92956

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints