TLE1 antibody (AA 199-228)

Catalog No. ABIN653567

The Rabbit Polyclonal anti-TLE1 antibody is suitable to detect TLE1 in samples from Human. It has been validated for WB.

Quick Overview for TLE1 antibody (AA 199-228) (ABIN653567)

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB23201

Product Details anti-TLE1 Antibody

Binding Specificity: AA 199-228

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-228 amino acids from the Central region of human TLE1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TLE1

Target: TLE1 (Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))

Alternative Name: TLE1

Background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Molecular Weight: 83201

Gene ID: 7088

NCBI Accession: NP_005068

UniProt: Q04724

Pathways: WNT Signaling, SARS-CoV-2 Protein Interactome