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WAP Four-Disulfide Core Domain 12 (WFDC12) (AA 66-94), (C-Term) antibody

Details for Product No. ABIN654327, Supplier: Log in to see
Antigen
  • C20orf122
  • SWAM2
  • WAP2
  • dJ211D12.4
  • Swam2
Epitope
AA 66-94, C-Term
17
16
1
Reactivity
Human
19
Host
Rabbit
19
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
17
15
15
15
2
1
Supplier
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Immunogen This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 AA from the C-terminal region of human WFDC12.
Clone RB27994
Isotype Ig
Specificity This WFDC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-102 amino acids from the C-terminal region of human WFDC12.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name WFDC12 (WFDC12 Antibody Abstract)
Background This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster.
Synonyms: WAP four-disulfide core domain protein 12,WFDC12,C20orf122, WAP2
Molecular Weight 12050 DA
Gene ID 128488
NCBI Accession NP_543145
UniProt Q8WWY7
Research Area Cell Signaling, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.33 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-WAP Four-Disulfide Core Domain 12 (WFDC12) (AA 66-94), (C-Term) antibody (ABIN654327) WFDC12 antibody (C-term) (ABIN654327) immunohistochemistry analysis in formalin fixed...
Background publications Clauss, Lilja, Lundwall: "The evolution of a genetic locus encoding small serine proteinase inhibitors." in: Biochemical and biophysical research communications, Vol. 333, Issue 2, pp. 383-9, 2005 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Clauss, Lilja, Lundwall: "A locus on human chromosome 20 contains several genes expressing protease inhibitor domains with homology to whey acidic protein." in: The Biochemical journal, Vol. 368, Issue Pt 1, pp. 233-42, 2002 (PubMed).

Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

Lundwall, Clauss: "Identification of a novel protease inhibitor gene that is highly expressed in the prostate." in: Biochemical and biophysical research communications, Vol. 290, Issue 1, pp. 452-6, 2002 (PubMed).