RNA Binding Motif Protein 14 (RBM14) (C-Term) antibody

Antigen: RNA Binding Motif Protein 14 (RBM14)

Synonyms: SIP, COAA, PSP2, SYTIP1, TMEM137, MGC15912, MGC31756, DKFZp779J0927, p16, p16K, Sytip, 1300007E16Rik, CoAA, im:7053198, wu:fc08a04, sip, coaa, psp2, sytip1, tmem137, MGC52864, MGC132117, MGC75876, rbm14, RBM14, RBM4, DKFZp469C2227

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655499

Additional Information

Alternative name: RBM14

Gene ID: 10432

UniProt: NP_006319.1, Q96PK6

Immunogen: This RBM14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 570-602 amino acids from the C-terminal region of human RBM14.

Isotype: Ig

Description: Other names: RNA-binding protein 14,RBM14,SIP

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This RBM14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 570-602 amino acids from the C-terminal region of human RBM14.

Molecular Weight: 69492 DA

Comments:

Background: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.

Synonyms: SIP, COAA, PSP2, SYTIP1, TMEM137, MGC15912, MGC31756, DKFZp779J0927, p16, p16K, Sytip, 1300007E16Rik, CoAA, im:7053198, wu:fc08a04, sip, coaa, psp2, sytip1, tmem137, MGC52864, MGC132117, MGC75876, rbm14, RBM14, RBM4, DKFZp469C2227

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure, Signaling, Protein Modifications, Chromatin, Phospho-specific antibodies, Transcription Factors, Translation Factors

Restrictions: For Research Use only

Images

RBM14 Antibody (C-term) (ABIN655499) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RBM14 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Publications

Product: Sugiyama, Masuda, Shinoda et al.: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, 2007 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Kang, Schiff, Ko et al.: "Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis." in: Cancer research, Vol. 68, Issue 19, pp. 7887-96, 2008 (PubMed).

Brooks, Wang, Yang et al.: "Functional pre- mRNA trans-splicing of coactivator CoAA and corepressor RBM4 during stem/progenitor cell differentiation." in: The Journal of biological chemistry, Vol. 284, Issue 27, pp. 18033-46, 2009 (PubMed).