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Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5) (AA 56-85), (N-Term) antibody

Details for Product No. ABIN655590, Supplier: Log in to see
Antigen
  • E030017K20
  • EG232801
  • Gm4878
  • Lilrc1
  • CD85m
  • ILT10
  • LILRA5
  • CD85
  • CD85F
  • ILT-11
  • ILT11
  • LILRB7
  • LIR-9
  • LIR9
Epitope
AA 56-85, N-Term
19
16
2
2
1
1
1
Reactivity
Human
30
3
1
Host
Rabbit
29
2
2
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
4
3
2
2
2
2
Application
Western Blotting (WB)
26
22
4
1
1
Supplier
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Immunogen This LILRA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 AA from the N-terminal region of human LILRA5.
Clone RB30159
Isotype Ig
Specificity This LILRA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human LILRA5.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LILRA5 (LILRA5 Antibody Abstract)
Background The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
Synonyms: Leukocyte immunoglobulin-like receptor subfamily A member 5,LILRA5,ILT11, LILRB7, LIR9
Molecular Weight 32755 DA
Gene ID 353514
NCBI Accession NP_871714, NP_871715, NP_067073, NP_870994
UniProt A6NI73
Research Area Cell Structure, Protein Modifications, Cell Signaling
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5) (AA 56-85), (N-Term) antibody (ABIN655590) LILRA5 Antibody (N-term) (ABIN655590) western blot analysis in MDA-MB435 cell line ly...
Background publications Shiroishi, Kajikawa, Kuroki et al.: "Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11)." in: The Journal of biological chemistry, Vol. 281, Issue 28, pp. 19536-44, 2006 (PubMed).

Borges, Kubin, Kuhlman: "LIR9, an immunoglobulin-superfamily-activating receptor, is expressed as a transmembrane and as a secreted molecule." in: Blood, Vol. 101, Issue 4, pp. 1484-6, 2003 (PubMed).

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