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Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8) (AA 519-548), (C-Term) antibody

Details for Product No. ABIN656431, Supplier: Log in to see
Antigen
  • AI132397
  • C21orf112
  • CCT8
  • Cctq
  • D21S246
  • DKFZp469C2223
  • fa22h09
  • MGC89698
  • PRED71
  • Tcpq
  • wu:fa22h09
  • zgc:56059
Epitope
AA 519-548, C-Term
19
16
7
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
63
23
13
6
4
3
3
2
2
2
2
Host
Rabbit
57
4
3
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
62
27
18
14
8
8
8
3
1
1
Supplier
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Immunogen This CCT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 AA from the C-terminal region of human CCT8.
Clone RB31130
Isotype Ig
Specificity This CCT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-548 amino acids from the C-terminal region of human CCT8.
Predicted Reactivity Mouse (Murine),Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CCT8 (CCT8 Antibody Abstract)
Background Molecular chaperone, CCT8 assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.
Synonyms: T-complex protein 1 subunit theta,CCT8,C21orf112, CCTQ, KIAA0002
Molecular Weight 59621 DA
Gene ID 10694
NCBI Accession NP_006576
UniProt P50990
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Protein Modifications, Chromatin, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment CCT8 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8) (AA 519-548), (C-Term) antibody (ABIN656431) CCT8 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).T...
Immunohistochemistry (IHC) image for anti-Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8) (AA 519-548), (C-Term) antibody (ABIN656431) CCT8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Flow Cytometry (FACS) image for anti-Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8) (AA 519-548), (C-Term) antibody (ABIN656431) CCT8 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) comp...
Background publications Zebol, Hewitt, Moretti, Lynn, Lake, Li, Vadas, Wattenberg, Pitson: "The CCT/TRiC chaperonin is required for maturation of sphingosine kinase 1." in: The international journal of biochemistry & cell biology, Vol. 41, Issue 4, pp. 822-7, 2009 (PubMed).

Kim, Sprung, Chen, Xu, Ball, Pei, Cheng, Kho, Xiao, Xiao, Grishin, White, Yang, Zhao: "Substrate and functional diversity of lysine acetylation revealed by a proteomics survey." in: Molecular cell, Vol. 23, Issue 4, pp. 607-18, 2006 (PubMed).

Wang, Zhu, Guo, Huo, Ma, Lin, Zhou, Sha: "A two-dimensional electrophoresis reference map of human ovary." in: Journal of molecular medicine (Berlin, Germany), Vol. 83, Issue 10, pp. 812-21, 2005 (PubMed).