Fukutin antibody (AA 177-206)

Catalog No. ABIN656713

Product Details anti-Fukutin Antibody

Target: Fukutin (FKTN)

Binding Specificity: AA 177-206

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fukutin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FKTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human FKTN.

Clone: RB31283

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: FKTN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for Fukutin

Target: Fukutin (FKTN)

Alternative Name: FKTN (FKTN Products)

Synonyms: FCMD antibody, fcmd antibody, im:7163166 antibody, zgc:162828 antibody, FKTN antibody, CMD1X antibody, LGMD2M antibody, MDDGA4 antibody, MDDGB4 antibody, MDDGC4 antibody, D830030O17Rik antibody, Fcmd antibody, fukutin antibody, fukutin S homeolog antibody, Fukutin antibody, FKTN antibody, fktn antibody, fktn.S antibody, Bm1_09375 antibody, Bm1_09380 antibody, Bm1_44655 antibody, Fktn antibody

Background: The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 53724

Gene ID: 2218

NCBI Accession: NP_001073270, NP_001185892, NP_006722

UniProt: O75072

Pathways: Regulation of Carbohydrate Metabolic Process