STARD5 antibody (N-Term)

Catalog No. ABIN656750

Product Details anti-STARD5 Antibody

Target: STARD5 (StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5))

Binding Specificity: AA 26-55, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STARD5 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This STARD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human STARD5.

Clone: RB32496

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: STARD5 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for STARD5

Target: STARD5 (StAR-Related Lipid Transfer (START) Domain Containing 5 (STARD5))

Alternative Name: STARD5 (STARD5 Products)

Synonyms: STARD5 antibody, MGC131265 antibody, DKFZp469N2125 antibody, 2310058G22Rik antibody, AI607880 antibody, D7Ertd152e antibody, RGD1561783 antibody, StAR related lipid transfer domain containing 5 antibody, StAR related lipid transfer domain containing 5 S homeolog antibody, StAR-related lipid transfer (START) domain containing 5 antibody, StAR-related lipid transfer domain containing 5 antibody, STARD5 antibody, stard5.S antibody, Stard5 antibody

Background: Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR, MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 [PubMed 12011452]).

Molecular Weight: 23794

Gene ID: 80765

NCBI Accession: NP_871629

UniProt: Q9NSY2

Pathways: Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process