ZCRB1 antibody (C-Term)

Catalog No. ABIN656856

The Rabbit Polyclonal anti-ZCRB1 antibody (Clone RB28117) (ABIN656856) specifically detects ZCRB1 in WB, FACS and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for ZCRB1 antibody (C-Term) (ABIN656856)

Target: ZCRB1 (Zinc Finger CCHC-Type and RNA Binding Motif 1 (ZCRB1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZCRB1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB28117

Product Details anti-ZCRB1 Antibody

Binding Specificity: AA 184-212, C-Term

Predicted Reactivity: B, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZCRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-212 amino acids from the C-terminal region of human ZCRB1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ZCRB1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for ZCRB1

Target: ZCRB1 (Zinc Finger CCHC-Type and RNA Binding Motif 1 (ZCRB1))

Alternative Name: ZCRB1

Background: Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.

Molecular Weight: 24592

Gene ID: 85437

NCBI Accession: NP_149105

UniProt: Q8TBF4