ZCRB1 antibody (C-Term)

Catalog No. ABIN955644

Product Details anti-ZCRB1 Antibody

Target: ZCRB1 (Zinc Finger CCHC-Type and RNA Binding Motif 1 (ZCRB1))

Binding Specificity: AA 183-212, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZCRB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ZCRB1 (C-term).

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse

Purification: Protein A column followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 183-212 amino acids from the C-terminal region of human ZCRB1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Target Details for ZCRB1

Target: ZCRB1 (Zinc Finger CCHC-Type and RNA Binding Motif 1 (ZCRB1))

Alternative Name: ZCRB1 (ZCRB1 Products)

Synonyms: MADP-1 antibody, madp1 antibody, rbm36 antibody, madp-1 antibody, zcchc19 antibody, MADP1 antibody, RBM36 antibody, SNRNP31 antibody, ZCCHC19 antibody, 2700088M22Rik antibody, Madp-1 antibody, RGD1309851 antibody, si:ch211-155a11.4 antibody, zgc:110711 antibody, zinc finger CCHC-type and RNA binding motif containing 1 antibody, zinc finger CCHC-type and RNA binding motif 1 antibody, zinc finger CCHC-type and RNA binding motif containing 1 L homeolog antibody, ZCRB1 antibody, zcrb1 antibody, Zcrb1 antibody, zcrb1.L antibody

Background: Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.Synonyms: Zinc finger CCHC-type and RNA-binding motif-containing protein 1

Gene ID: 85437

NCBI Accession: NP_149105