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Details for Product No. ABIN656884

Single-Minded Homolog 1 (Drosophila) (SIM1) (N-Term), (AA 1-30) antibody

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Antigen
Synonyms mSIM1, bHLHe14
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN656884
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This SIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human SIM1.
Clone RB32160
Isotype Ig
Specificity This SIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SIM1.
Predicted Reactivity Fruit Fly (Drosophila melanogaster),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SIM1
Background SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.
Synonyms: Single-minded homolog 1,SIM1,BHLHE14
Molecular Weight 85515 DA
Gene ID 6492
UniProt P81133, NP_005059.2
Research Area Cell Cycle, Transcription Factors, Signaling, Neurology, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Concentration 0.38 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment SIM1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Traurig, Mack, Hanson et al.: "Common variation in SIM1 is reproducibly associated with BMI in Pima Indians." in: Diabetes, Vol. 58, Issue 7, pp. 1682-9, 2009 (PubMed).

Alternatives for antigen "Single-Minded Homolog 1 (Drosophila) (SIM1)", type "Antibodies"
Hosts (21), (3)
Reactivities (24), (15), (15), (15), (15), (15), (14), (2)
Applications (13), (10), (7), (7), (4), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (4), (3), (1)
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