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Details for Product No. ABIN657120

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12) (AA 723-752), (Center) antibody

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Antigen
Synonyms 4930467B22Rik, MRP9
Epitope
»Alternatives AA 723-752, Center
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN657120
Quantity 400 ┬ÁL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 723-752 AA from the Central region of human ABCC12.
Clone RB32878
Isotype Ig
Specificity This ABCC12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 722-751 amino acids from the Central region of human ABCC12.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ABCC12
Background This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
Synonyms: Multidrug resistance-associated protein 9,ABCC12,MRP9
Research Area Protein Modifications, Cell Structure, Signaling, Chromatin
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Yabuuchi, Shimizu, Takayanagi et al.: "Multiple splicing variants of two new human ATP-binding cassette transporters, ABCC11 and ABCC12." in: Biochemical and biophysical research communications, Vol. 288, Issue 4, pp. 933-9, 2001 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Alternatives for antigen "ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 12 (ABCC12)", type "Antibodies"
Hosts (23), (8), (6)
Reactivities (31), (17), (14), (13), (12), (1)
Applications (26), (14), (10), (8), (6), (4), (4), (4), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (2), (2), (1), (1), (1), (1)
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