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FOXA2 antibody (Forkhead Box A2) (AA 134-163)

Details for Product anti-FOXA2 Antibody No. ABIN657130, Supplier: Log in to see
Antigen
  • ax
  • axl
  • fkd1
  • FOXA2
  • FoxA2-A
  • FoxA2a
  • Hnf-3b
  • HNF-3b
  • HNF-3B
  • HNF-3BETA
  • hnf3-beta
  • HNF3-beta
  • Hnf3b
  • HNF3B
  • hnf3b
  • hnf3beta
  • HNF3beta
  • ik:tdsubc_2g8
  • Tcf-3b
  • TCF3B
  • Tcf3b
  • tcf3b
  • tdsubc_2g8
  • wu:fe05g04
  • xbeta-1
  • xFD-3
  • xx:tdsubc_2g8
Epitope
AA 134-163, Center, Thr156
36
30
21
18
15
14
13
12
8
8
5
3
3
3
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human
180
30
30
5
2
1
1
1
1
1
1
1
1
Host
Rabbit
98
65
22
Clonality (Clone)
Polyclonal ()
Conjugate
This FOXA2 antibody is un-conjugated
9
8
8
8
7
7
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
164
116
81
48
31
16
14
13
12
6
1
1
1
1
Supplier
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Supplier Product No.
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Immunogen This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 134-163 AA from the Central region of human FOXA2.
Clone RB32955
Isotype Ig
Specificity This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Central region of human FOXA2.
Predicted Reactivity Mouse (Murine),Rat (Rattus),Xenopus laevis,Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FOXA2 (FOXA2 Antibody Abstract)
Background This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
Synonyms: Hepatocyte nuclear factor 3-beta,FOXA2,HNF3B, TCF3B
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Immunohistochemistry (IHC) image for anti-FOXA2 antibody (Forkhead Box A2) (AA 134-163) (ABIN657130) FOXA2 Antibody (Center T156) (ABIN657130) immunohistochemistry analysis in formalin f...
Background publications Dayoub, Groitl, Dobner, Bosserhoff, Schlitt, Weiss: "Foxa2 (HNF-3beta) regulates expression of hepatotrophic factor ALR in liver cells." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 465-70, 2010 (PubMed).

Xing, Cohen, Boerwinkle: "A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels." in: American journal of human genetics, Vol. 86, Issue 3, pp. 440-6, 2010 (PubMed).

Song, Washington, Crawford: "Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2115-25, 2010 (PubMed).