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Details for Product No. ABIN657143

AFG3 ATPase Family Gene 3-Like 2 (S. Cerevisiae) (AFG3L2) (N-Term), (AA 52-80) antibody

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Antigen
Synonyms SCA28, SPAX5, par, Emv66, AW260507, 2310036I02Rik, si:ch211-12e1.4, MGC147390
Epitope
»Alternatives N-Term, AA 52-80
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN657143
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This AFG3L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 AA from the N-terminal region of human AFG3L2.
Clone RB33011
Isotype Ig
Specificity This AFG3L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-80 amino acids from the N-terminal region of human AFG3L2.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name AFG3L2
Background This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. This gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders.
Synonyms: AFG3-like protein 2,AFG3L2,
Research Area Signaling, Protein Modifications, Cell Structure, Chromatin, Neurology, Metabolism
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Background publications Augustin, Gerdes, Lee et al.: "An intersubunit signaling network coordinates ATP hydrolysis by m-AAA proteases." in: Molecular cell, Vol. 35, Issue 5, pp. 574-85, 2009 (PubMed).

Di Bella, Lazzaro, Brusco et al.: "Mutations in the mitochondrial protease gene AFG3L2 cause dominant hereditary ataxia SCA28." in: Nature genetics, Vol. 42, Issue 4, pp. 313-21, 2010 (PubMed).

Edener, Wöllner, Hehr et al.: "Early onset and slow progression of SCA28, a rare dominant ataxia in a large four-generation family with a novel AFG3L2 mutation." in: European journal of human genetics : EJHG, Vol. 18, Issue 8, pp. 965-8, 2010 (PubMed).

Alternatives for antigen "AFG3 ATPase Family Gene 3-Like 2 (S. Cerevisiae) (AFG3L2)", type "Antibodies"
Hosts (25), (2)
Reactivities (26), (15), (15), (13), (13), (13), (12), (1), (1)
Applications (18), (11), (10), (4), (4), (2), (1)
Conjugates (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (1), (1), (1), (1), (1), (1)
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