AFG3L2 antibody (AA 550-759)

Catalog No. ABIN7143582

Product Details anti-AFG3L2 Antibody

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Binding Specificity: AA 550-759

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFG3L2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human AFG3-like protein 2 protein (550-759AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AFG3L2

Target: AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

Alternative Name: AFG3L2 (AFG3L2 Products)

Synonyms: MGC147390 antibody, si:ch211-12e1.4 antibody, SCA28 antibody, SPAX5 antibody, 2310036I02Rik antibody, AW260507 antibody, Emv66 antibody, par antibody, AFG3 like matrix AAA peptidase subunit 2 antibody, AFG3-like protein 2 antibody, AFG3 ATPase family gene 3-like 2 (S. cerevisiae) antibody, AFG3-like AAA ATPase 2 antibody, AFG3-like AAA ATPase 2 L homeolog antibody, AFG3L2 antibody, LOC578526 antibody, afg3l2 antibody, afg3l2.L antibody, Afg3l2 antibody

Background:

Background: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).

Aliases: AFG3 (ATPase family gene 3, yeast) like 2 antibody, AFG3 ATPase family gene 3 like 2 (yeast) antibody, AFG3 ATPase family gene 3 like 2 antibody, AFG3 like protein 2 antibody, AFG3-like protein 2 antibody, AFG32_HUMAN antibody, AFG3L2 antibody, ATPase family gene 3 like 2 antibody, ATPase family gene 3 yeast antibody, EC 3.4.24.- antibody, FLJ25993 antibody, Paraplegin like protein antibody, Paraplegin-like protein antibody, SCA28 antibody, Spinocerebellar ataxia 28 antibody

UniProt: Q9Y4W6

Pathways: Skeletal Muscle Fiber Development