You are viewing an incomplete version of our website. Please click to reload the website as full version.

PHD Finger Protein 17 (PHF17) (AA 22-51), (N-Term) antibody

Details for Product No. ABIN657355, Supplier: Login to see New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Synonyms fi11a04, jade1, wu:fi11a04, zgc:55323, JADE1, AU041499, D530048A03Rik, Jade1, mKIAA1807
AA 22-51, N-Term
(18), (15), (5), (2), (1), (1), (1), (1), (1), (1)
Mouse (Murine)
(24), (22), (8), (3), (3), (2), (2), (1), (1)
(35), (2)
Clonality (Clone)
Polyclonal ()
(2), (2), (2), (2), (2), (2)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(35), (17), (16), (4), (3), (1), (1), (1)
Pubmed 5 references available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This PHF17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 AA from the N-terminal region of human PHF17.
Clone RB15092
Isotype Ig
Specificity This PHF17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-51 amino acids from the N-terminal region of human PHF17.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name PHF17 (PHF17 Antibody Abstract)
Background Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
Synonyms: Protein Jade-1,PHF17,JADE1, KIAA1807
Molecular Weight 95533 DA
Gene ID 79960
NCBI Accession NP_955352, NP_079176
UniProt Q6IE81
Research Area Apoptosis/Necrosis, Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment PHF17 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-PHD Finger Protein 17 (PHF17) (AA 22-51), (N-Term) antibody (ABIN657355) PHF17 Antibody (N-term) (ABIN657355) western blot analysis in mouse heart tissue lysa...
Background publications Chitalia, Foy, Bachschmid et al.: "Jade-1 inhibits Wnt signalling by ubiquitylating beta-catenin and mediates Wnt pathway inhibition by pVHL." in: Nature cell biology, Vol. 10, Issue 10, pp. 1208-16, 2008 (PubMed).

Foy, Song, Chitalia et al.: "Role of Jade-1 in the histone acetyltransferase (HAT) HBO1 complex." in: The Journal of biological chemistry, Vol. 283, Issue 43, pp. 28817-26, 2008 (PubMed).

Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Lim, Hao, Shaw et al.: "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration." in: Cell, Vol. 125, Issue 4, pp. 801-14, 2006 (PubMed).

Doyon, Cayrou, Ullah et al.: "ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation." in: Molecular cell, Vol. 21, Issue 1, pp. 51-64, 2006 (PubMed).

Catalog No. ABIN657355
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)