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Nedd4 Family Interacting Protein 1 (NDFIP1) (AA 77-106), (Center) antibody

Details for Product No. ABIN657372
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Antigen
Epitope
AA 77-106, Center
(15), (8), (7), (2), (1), (1)
Reactivity
Human
(24), (19), (5), (1), (1)
Host
Rabbit
(21), (7), (3), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(31), (26), (2), (1), (1)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN657372
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Immunogen This NDFIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-106 AA from the Central region of human NDFIP1.
Clone RB32776
Isotype Ig
Specificity This NDFIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-106 amino acids from the Central region of human NDFIP1.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NDFIP1
Background The protein encoded by this gene belongs to a small group of evolutionarily conserved proteins with three transmembrane domains. It is a potential target for ubiquitination by the Nedd4 family of proteins. This protein is thought to be part of a family of integral Golgi membrane proteins.
Synonyms: NEDD4 family-interacting protein 1,NDFIP1,N4WBP5
Molecular Weight 24899 DA
Gene ID 80762
UniProt Q9BT67, NP_085048.1
Research Area Ubiquitin-related antibodies, Cell Structure, Protein Modifications, Chromatin, Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment NDFIP1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Nedd4 Family Interacting Protein 1 (NDFIP1) (AA 77-106), (Center) antibody NDFIP1 Antibody (Center) (ABIN657372) western blot analysis in human normal Uterus cell line lysates (35 µg/lane). This demonstrates the NDFIP1 antibody detected the NDFIP1 protein (arrow).
Background publications Rapley, Turnbull, Al Olama et al.: "A genome-wide association study of testicular germ cell tumor." in: Nature genetics, Vol. 41, Issue 7, pp. 807-10, 2009 (PubMed).

Howitt, Putz, Lackovic et al.: "Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 36, pp. 15489-94, 2009 (PubMed).

Mund, Pelham: "Regulation of PTEN/Akt and MAP kinase signaling pathways by the ubiquitin ligase activators Ndfip1 and Ndfip2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 25, pp. 11429-34, 2010 (PubMed).

Validation Images
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