Adhesion Molecule with Ig-Like Domain 1 (AMIGO1) (C-Term) antibody

Antigen: Adhesion Molecule with Ig-Like Domain 1 (AMIGO1)

Binding Site: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN657604

Additional Information

Alternative name: AMIGO1

Gene ID: 57463

UniProt: Q86WK6, NP_065754.2

Immunogen: This AMIGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the C-terminal region of human AMIGO1.

Isotype: Ig

Description: Other names: Amphoterin-induced protein 1,AMIGO1,ALI2, AMIGO, KIAA1163

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This AMIGO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 amino acids from the C-terminal region of human AMIGO1.

Molecular Weight: 55239 DA

Comments:

Background: AMIGO1 promotes growth and fasciculation of neurites from cultured hippocampal neurons. May be involved in fasciculation as well as myelination of developing neural axons. May have a role in regeneration as well as neural plasticity in the adult nervous system. May mediate homophilic as well as heterophilic cell-cell interaction and contribute to signal transduction through its intracellular domain (By similarity).

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: AMIGO1 Antibody (C-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Cell Cycle, Neurology

Restrictions: For Research Use only

Images

AMIGO1 Antibody (C-term) (ABIN657604) western blot analysis in HepG2 cell line lysates (35ug/lane). This demonstrates the AMIGO1 antibody detected the AMIGO1 protein (arrow).

Publications

Product: Kuja-Panula, Kiiltomäki, Yamashiro et al.: "AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats." in: The Journal of cell biology, Vol. 160, Issue 6, pp. 963-73, 2003 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Köttgen, Pattaro, Böger et al.: "New loci associated with kidney function and chronic kidney disease." in: Nature genetics, Vol. 42, Issue 5, pp. 376-84, 2010 (PubMed).